Product Data Sheet
(+/-)-Adomeglivant ((+/-)-LY2409021)
Catalog No. A74260
(+/-)-Adomeglivant is a selective glucagon receptor antagonist that exerts hypoglycemic effects by inhibiting glucagon signaling. This compound is effective in lowering blood glucose levels in both healthy individuals and patients with type 2 diabetes. Its use has been associated with a reduction in fasting and postprandial glucose, alongside a reversible increase in aminotransferases. The potential of (+/-)-Adomeglivant as an inhibitory approach in the management of type 2 diabetes merits further investigation in clinical studies to fully assess its benefits and risks.
Chemical Information
| Catalog Num | A74260 |
|---|---|
| M. Wt | 555.63 |
| Formula | C32H36F3NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 872260-47-4 |
| Synonyms | (+/-)-LY2409021 |
| SMILES | O=C(CCNC(C1=CC=C(C(CCC(F)(F)F)OC2=CC(C)=C(C3=CC=C(C(C)(C)C)C=C3)C(C)=C2)C=C1)=O)O |
Biological Activity
| Description | (+/-)-Adomeglivant is a selective glucagon receptor antagonist that exerts hypoglycemic effects by inhibiting glucagon signaling. This compound is effective in lowering blood glucose levels in both healthy individuals and patients with type 2 diabetes. Its use has been associated with a reduction in fasting and postprandial glucose, alongside a reversible increase in aminotransferases. The potential of (+/-)-Adomeglivant as an inhibitory approach in the management of type 2 diabetes merits further investigation in clinical studies to fully assess its benefits and risks. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
