Product Data Sheet
(R,R,S)-GAT107
Catalog No. A74280
(R,R,S)-GAT107 is a potent positive allosteric modulator of the α7 nicotinic receptors, exhibiting robust agonistic activity. This compound primarily functions through its (+)-isomer, demonstrating significant biological effects, while the (-)-isomer shows no such activity. Research indicates that (R,R,S)-GAT107 is currently recognized as the most effective ago-PAM for α7 nicotinic receptors, suggesting promising avenues for further investigation in vivo. Potential applications include studies related to cognitive enhancement and neuroinflammation.
Chemical Information
| Catalog Num | A74280 |
|---|---|
| M. Wt | 405.31 |
| Formula | C18H17BrN2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1426240-47-2 |
| Synonyms | |
| SMILES | NS(=O)(C1=CC=C2N[C@@H](C3=CC=C(C=C3)Br)[C@](CC=C4)([H])[C@]4([H])C2=C1)=O |
Biological Activity
| Description | (R,R,S)-GAT107 is a potent positive allosteric modulator of the α7 nicotinic receptors, exhibiting robust agonistic activity. This compound primarily functions through its (+)-isomer, demonstrating significant biological effects, while the (-)-isomer shows no such activity. Research indicates that (R,R,S)-GAT107 is currently recognized as the most effective ago-PAM for α7 nicotinic receptors, suggesting promising avenues for further investigation in vivo. Potential applications include studies related to cognitive enhancement and neuroinflammation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
