Product Data Sheet

(+)-Adomeglivant (d-Adomeglivant)

Catalog No. A74285

main product photo
(+)-Adomeglivant is a selective antagonist of the glycogenotropin receptor, exhibiting significant glucose-lowering activity. Its ability to effectively reduce fasting blood glucose levels makes it a valuable tool for studying hyperglycemia mechanisms in type 2 diabetes. Additionally, the antagonistic properties of (+)-Adomeglivant may complicate assessments of the metabolic effects associated with postprandial hyperglycemia, providing insights into the intricacies of metabolic regulation in diabetic conditions.
Chemical Information
Catalog NumA74285
M. Wt555.63
FormulaC32H36F3NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.872260-19-0
Synonyms(+)-LY2409021
SMILESO=C(O)CCNC(C1=CC=C([C@H](OC2=CC(C)=C(C3=CC=C(C(C)(C)C)C=C3)C(C)=C2)CCC(F)(F)F)C=C1)=O
Biological Activity
Description(+)-Adomeglivant is a selective antagonist of the glycogenotropin receptor, exhibiting significant glucose-lowering activity. Its ability to effectively reduce fasting blood glucose levels makes it a valuable tool for studying hyperglycemia mechanisms in type 2 diabetes. Additionally, the antagonistic properties of (+)-Adomeglivant may complicate assessments of the metabolic effects associated with postprandial hyperglycemia, providing insights into the intricacies of metabolic regulation in diabetic conditions.
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