Product Data Sheet

DL-4-Hydroxy-2-ketoglutarate

Catalog No. A74340

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DL-4-Hydroxy-2-ketoglutarate acts as a substrate for the enzymes glutamic oxalacetic aminotransferase (GOT) and 2-keto-4-hydroxyglutarate aldolase, mediating the reversible conversion of 2-keto-4-hydroxyglutarate to pyruvate and glyoxylate. This endogenous metabolite is valuable in mass spectrometry applications for the rapid analysis of negatively charged, water-soluble cellular metabolites, aiding in metabolic pathway studies and biomarker discovery.
Chemical Information
Catalog NumA74340
M. Wt162.10
FormulaC5H6O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1187-99-1
Synonyms
SMILESO=C(C(CC(C(O)=O)O)=O)O
Biological Activity
DescriptionDL-4-Hydroxy-2-ketoglutarate acts as a substrate for the enzymes glutamic oxalacetic aminotransferase (GOT) and 2-keto-4-hydroxyglutarate aldolase, mediating the reversible conversion of 2-keto-4-hydroxyglutarate to pyruvate and glyoxylate. This endogenous metabolite is valuable in mass spectrometry applications for the rapid analysis of negatively charged, water-soluble cellular metabolites, aiding in metabolic pathway studies and biomarker discovery.
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