Product Data Sheet
Oleic Acid-2,6-diisopropylanilide
Catalog No. A74352
Oleic Acid-2,6-diisopropylanilide is a potent inhibitor of acylCoA:cholesterol acyltransferase (ACAT), a key enzyme involved in the synthesis of cholesteryl esters related to dietary cholesterol absorption, with an IC50 of 7 nM. This compound has demonstrated biological activity by lowering low-density lipoproteins and increasing high-density lipoprotein levels in animal models subjected to high-fat, high-cholesterol diets. It serves as a valuable tool in research applications focused on lipid metabolism and cardiovascular disease.
Chemical Information
| Catalog Num | A74352 |
|---|---|
| M. Wt | 441.73 |
| Formula | C30H51NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 140112-65-8 |
| Synonyms | |
| SMILES | CC(C1=C(C(C(C)C)=CC=C1)N(C(CCCCCCC/C=C\CCCCCCCC)=O)[H])C |
Biological Activity
| Description | Oleic Acid-2,6-diisopropylanilide is a potent inhibitor of acylCoA:cholesterol acyltransferase (ACAT), a key enzyme involved in the synthesis of cholesteryl esters related to dietary cholesterol absorption, with an IC50 of 7 nM. This compound has demonstrated biological activity by lowering low-density lipoproteins and increasing high-density lipoprotein levels in animal models subjected to high-fat, high-cholesterol diets. It serves as a valuable tool in research applications focused on lipid metabolism and cardiovascular disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
