Product Data Sheet

Thymine-13C5,15N,15N2

Catalog No. A74369

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Thymine-13C5,15N2 is a stable isotope-labeled form of thymine, incorporating five carbon-13 and two nitrogen-15 isotopes. Thymine, a key nucleobase in DNA, plays a critical role in nucleic acid synthesis and is a potential target for therapeutic interventions, including the chemotherapeutic agent, 5-fluorouracil, which exhibits a Km of 2.3 μM. This reagent is valuable for metabolic studies, tracer experiments, and the investigation of nucleotide metabolism in various biological and pathological contexts.
Chemical Information
Catalog NumA74369
M. Wt133.06
Formula13C5H615N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2483830-13-1
Synonyms5-Methyluacil-13C5,15N,15N2
SMILESO=[13C]1[13C]([13CH3])=[13CH][15NH][13C]([15NH]1)=O
Biological Activity
DescriptionThymine-13C5,15N2 is a stable isotope-labeled form of thymine, incorporating five carbon-13 and two nitrogen-15 isotopes. Thymine, a key nucleobase in DNA, plays a critical role in nucleic acid synthesis and is a potential target for therapeutic interventions, including the chemotherapeutic agent, 5-fluorouracil, which exhibits a Km of 2.3 μM. This reagent is valuable for metabolic studies, tracer experiments, and the investigation of nucleotide metabolism in various biological and pathological contexts.
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SHIPPING AND STORAGE
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