Product Data Sheet
(+/-)13-HODE cholesteryl ester
Catalog No. A74487
(+/-) 13-HODE cholesteryl ester is an endogenous metabolite derived from atherosclerotic lesions, produced through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL). It is synthesized by the action of lipoxygenase enzymes, particularly 15-lipoxygenase from rabbit reticulocytes and human monocytes, acting on cholesteryl linoleate, a key component of LDL. This compound is essential for studying lipid metabolism and the pathophysiological mechanisms involved in atherosclerosis and related cardiovascular conditions.
Chemical Information
| Catalog Num | A74487 |
|---|---|
| M. Wt | 665.08 |
| Formula | C₄₅H₇₆O₃ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 167354-91-8 |
| Synonyms | |
| SMILES | CCCCCC(O)/C=C/C=C\CCCCCCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@@]4(C)[C@](CC[C@]4([H])[C@@H](CCCC(C)C)C)([H])[C@]3([H])CC=C2C1)=O |
Biological Activity
| Description | (+/-) 13-HODE cholesteryl ester is an endogenous metabolite derived from atherosclerotic lesions, produced through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL). It is synthesized by the action of lipoxygenase enzymes, particularly 15-lipoxygenase from rabbit reticulocytes and human monocytes, acting on cholesteryl linoleate, a key component of LDL. This compound is essential for studying lipid metabolism and the pathophysiological mechanisms involved in atherosclerosis and related cardiovascular conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
