Product Data Sheet

AKU-005

Catalog No. A74633

main product photo
AKU-005 is a dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), exhibiting IC50 values of 63 nM and 389 nM for rat and human FAAH, respectively. This compound demonstrates significant potential in the study of trigeminal hyperalgesia and related pain pathways, making it a valuable tool for researchers investigating endocannabinoid signaling and pain modulation mechanisms.
Chemical Information
Catalog NumA74633
M. Wt347.41
FormulaC20H21N5O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1515855-85-2
Synonyms
SMILESO=C(N1C=NC=N1)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4
Biological Activity
DescriptionAKU-005 is a dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), exhibiting IC50 values of 63 nM and 389 nM for rat and human FAAH, respectively. This compound demonstrates significant potential in the study of trigeminal hyperalgesia and related pain pathways, making it a valuable tool for researchers investigating endocannabinoid signaling and pain modulation mechanisms.
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