Product Data Sheet
Irafamdastat
Catalog No. A74637
Irafamdastat is a potent inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), exhibiting IC50 values of ≤ 100 nM for human FAAH and 100 nM-1 µM for human MAGL. This compound has demonstrated antiepileptic effects and is valuable for research into pain management, neuroprotection, and anxiety. Its dual inhibition of FAAH and MAGL positions it as a significant tool for exploring endocannabinoid system modulation in various therapeutic contexts.
Chemical Information
| Catalog Num | A74637 |
|---|---|
| M. Wt | 438.40 |
| Formula | C20H21F3N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2244136-58-9 |
| Synonyms | BMS-986368; CC-97489; ABX-1772 |
| SMILES | NC(C1=CC(OC(N2[C@@H](CN(CC2)CC3=CC(OC(F)(F)F)=CC=C3)C)=O)=CN=C1)=O |
Biological Activity
| Description | Irafamdastat is a potent inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), exhibiting IC50 values of ≤ 100 nM for human FAAH and 100 nM-1 µM for human MAGL. This compound has demonstrated antiepileptic effects and is valuable for research into pain management, neuroprotection, and anxiety. Its dual inhibition of FAAH and MAGL positions it as a significant tool for exploring endocannabinoid system modulation in various therapeutic contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
