Product Data Sheet
FAAH/MAGL-IN-2
Catalog No. A74653
FAAH/MAGL-IN-2 is a potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). It exhibits IC50 values of 11 nM and 36 nM for FAAH and MAGL, respectively, demonstrating significant inhibitory potency. This compound effectively crosses the blood-brain barrier, making it a valuable tool for investigating the role of endogenous lipids in neuropathic pain while minimizing locomotion impairment. Its selective inhibition profile facilitates research into therapeutic approaches for pain management and related disorders.
Chemical Information
| Catalog Num | A74653 |
|---|---|
| M. Wt | 386.25 |
| Formula | C15H13Cl2N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2765077-82-3 |
| Synonyms | |
| SMILES | O=C(N/N=C\C1=C(Cl)C=CC=C1Cl)NC2=CC=C(S(=O)(C)=O)C=C2 |
Biological Activity
| Description | FAAH/MAGL-IN-2 is a potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). It exhibits IC50 values of 11 nM and 36 nM for FAAH and MAGL, respectively, demonstrating significant inhibitory potency. This compound effectively crosses the blood-brain barrier, making it a valuable tool for investigating the role of endogenous lipids in neuropathic pain while minimizing locomotion impairment. Its selective inhibition profile facilitates research into therapeutic approaches for pain management and related disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
