Product Data Sheet
AZ513
Catalog No. A74672
AZ513 is a reversible inhibitor of fatty acid amide hydrolase (FAAH), exhibiting IC50 values of 551 nM for human FAAH and 27 nM for rat FAAH. This compound effectively inhibits the hydrolysis of anandamide in human FAAH-transfected HEK293 cells, demonstrating an IC50 of 360 nM. AZ513 is suitable for research applications focusing on the modulation of endocannabinoid signaling pathways and the study of pain relief and neuroprotection mechanisms.
Chemical Information
| Catalog Num | A74672 |
|---|---|
| M. Wt | 306.15 |
| Formula | C14H9Cl2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1335231-15-6 |
| Synonyms | |
| SMILES | O=C(C1=C(Cl)C(Cl)=CC=C1)NC2=CC3=C(NC=C3)N=C2 |
Biological Activity
| Description | AZ513 is a reversible inhibitor of fatty acid amide hydrolase (FAAH), exhibiting IC50 values of 551 nM for human FAAH and 27 nM for rat FAAH. This compound effectively inhibits the hydrolysis of anandamide in human FAAH-transfected HEK293 cells, demonstrating an IC50 of 360 nM. AZ513 is suitable for research applications focusing on the modulation of endocannabinoid signaling pathways and the study of pain relief and neuroprotection mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
