Product Data Sheet
Apixaban-13C,d3
Catalog No. A74707
Apixaban-13C,d3 is a stable isotope-labeled derivative of Apixaban, a potent and selective reversible inhibitor of Factor Xa, exhibiting Ki values of 0.08 nM and 0.17 nM in human and rabbit models, respectively. This high specificity makes Apixaban ideal for investigating anticoagulant mechanisms and studying related pharmacological effects. Researchers can utilize Apixaban-13C,d3 for quantitative analysis in pharmacokinetic studies, metabolic profiling, and isotopic tracing in biochemical assays.
Chemical Information
| Catalog Num | A74707 |
|---|---|
| M. Wt | 463.51 |
| Formula | C2413CH22D3N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1261393-15-0 |
| Synonyms | BMS-562247-01-13C,d3 |
| SMILES | NC(C1=NN(C2=C1CCN(C2=O)C3=CC=C(C=C3)N4CCCCC4=O)C5=CC=C(C=C5)O[13C]([2H])([2H])[2H])=O |
Biological Activity
| Description | Apixaban-13C,d3 is a stable isotope-labeled derivative of Apixaban, a potent and selective reversible inhibitor of Factor Xa, exhibiting Ki values of 0.08 nM and 0.17 nM in human and rabbit models, respectively. This high specificity makes Apixaban ideal for investigating anticoagulant mechanisms and studying related pharmacological effects. Researchers can utilize Apixaban-13C,d3 for quantitative analysis in pharmacokinetic studies, metabolic profiling, and isotopic tracing in biochemical assays. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
