Product Data Sheet

FXIa-IN-7

Catalog No. A74717

main product photo
FXIa-IN-7 is a selective, orally bioavailable inhibitor of Factor XIa, exhibiting an impressive IC50 value of 0.4 nM. This compound demonstrates potent antithrombotic potential, making it a valuable tool for research in coagulation pathways and thrombotic disorders. Its specificity towards Factor XIa positions FXIa-IN-7 as an important reagent for studies aimed at understanding the role of the intrinsic pathway in hemostasis and thrombosis.
Chemical Information
Catalog NumA74717
M. Wt456.53
FormulaC28H28N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2488952-56-1
Synonyms
SMILESO=C(C1=CC=CC2=C1N(C[C@H](C3=CC(C(C)C)=CC(C4=CC=C(OC[C@H]5N)C5=C4)=C3)O)C=C2)O
Biological Activity
DescriptionFXIa-IN-7 is a selective, orally bioavailable inhibitor of Factor XIa, exhibiting an impressive IC50 value of 0.4 nM. This compound demonstrates potent antithrombotic potential, making it a valuable tool for research in coagulation pathways and thrombotic disorders. Its specificity towards Factor XIa positions FXIa-IN-7 as an important reagent for studies aimed at understanding the role of the intrinsic pathway in hemostasis and thrombosis.
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