Product Data Sheet

Linafexor

Catalog No. A74875

main product photo
Linafexor is a potent FXR ( Farnesoid X Receptor) agonist that modulates bile acid homeostasis. By activating FXR, it plays a crucial role in regulating liver function. This compound is particularly relevant for research on primary sclerosing cholangitis (PSC) and metabolic dysfunction-associated steatohepatitis (MASH), offering insights into therapeutic strategies for liver-related diseases.
Chemical Information
Catalog NumA74875
M. Wt571.43
FormulaC28H25Cl2FN4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2765593-43-7
SynonymsCS-0159
SMILESClC(C=CC=C1Cl)=C1C2=NOC(C3CC3)=C2CO[C@@H]4C[C@@]5([H])N(C6=CC(F)=C(C7=NOC(N7)=O)C=C6)[C@@](CC5)([H])C4
Biological Activity
DescriptionLinafexor is a potent FXR ( Farnesoid X Receptor) agonist that modulates bile acid homeostasis. By activating FXR, it plays a crucial role in regulating liver function. This compound is particularly relevant for research on primary sclerosing cholangitis (PSC) and metabolic dysfunction-associated steatohepatitis (MASH), offering insights into therapeutic strategies for liver-related diseases.
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