Product Data Sheet
(E)-GW 4064
Catalog No. A74903
(E)-GW 4064 is a potent agonist of the farnesoid X receptor (FXR), a nuclear receptor that plays a crucial role in lipid and glucose metabolism. This compound has demonstrated significant biological activity in regulating bile acid synthesis and glucose homeostasis, making it a valuable tool for investigating metabolic disorders. Research applications include studying the effects of FXR activation on metabolic pathways and exploring its potential therapeutic benefits in conditions such as obesity and diabetes.
Chemical Information
| Catalog Num | A74903 |
|---|---|
| M. Wt | 542.84 |
| Formula | C28H22Cl3NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1089660-72-9 |
| Synonyms | |
| SMILES | ClC(C=C1OCC2=C(C(C)C)ON=C2C3=C(C=CC=C3Cl)Cl)=C(C=C1)/C=C/C4=CC(C(O)=O)=CC=C4 |
Biological Activity
| Description | (E)-GW 4064 is a potent agonist of the farnesoid X receptor (FXR), a nuclear receptor that plays a crucial role in lipid and glucose metabolism. This compound has demonstrated significant biological activity in regulating bile acid synthesis and glucose homeostasis, making it a valuable tool for investigating metabolic disorders. Research applications include studying the effects of FXR activation on metabolic pathways and exploring its potential therapeutic benefits in conditions such as obesity and diabetes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
