Product Data Sheet
GSK2324
Catalog No. A74915
GSK2324 is a selective agonist of the farnesoid X receptor (FXR), demonstrating an EC50 of 120 nM. This compound is predominantly utilized in diabetes research, where it plays a pivotal role in the modulation of metabolic processes. Pharmacokinetic studies reveal half-life values of 84 minutes in mice, 170 minutes in rats, 110 minutes in beagle dogs, and 120 minutes in cynomolgus monkeys, indicating its potential for translational studies.
Chemical Information
| Catalog Num | A74915 |
|---|---|
| M. Wt | 533.40 |
| Formula | C29H22Cl2N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1020567-30-9 |
| Synonyms | |
| SMILES | O=C(C1=NC2=CC=C(C3=CC=C(OCC4=C(C(C)C)ON=C4C5=C(Cl)C=CC=C5Cl)C=C3)C=C2C=C1)O |
Biological Activity
| Description | GSK2324 is a selective agonist of the farnesoid X receptor (FXR), demonstrating an EC50 of 120 nM. This compound is predominantly utilized in diabetes research, where it plays a pivotal role in the modulation of metabolic processes. Pharmacokinetic studies reveal half-life values of 84 minutes in mice, 170 minutes in rats, 110 minutes in beagle dogs, and 120 minutes in cynomolgus monkeys, indicating its potential for translational studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
