Product Data Sheet

FXR antagonist 3

Catalog No. A74920

main product photo
FXR antagonist 3 is a selective antagonist of the farnesoid X receptor (FXR) with an IC50 of 0.89 μM. This compound exhibits notable activity in modulating intestinal FXR signaling pathways, making it valuable for research related to metabolic disease and bile acid regulation. It serves as a useful tool in studying the physiological roles of FXR in gastrointestinal disorders and potential therapeutic interventions.
Chemical Information
Catalog NumA74920
M. Wt512.64
FormulaC32H36N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3024652-96-5
Synonyms
SMILESO=C(OCC)C1=CC=C(CNC(CC2=CC=C(N(CC3=CC=CC(C)=C3)C(C4CCCC4)=O)C=C2)=O)C=C1
Biological Activity
DescriptionFXR antagonist 3 is a selective antagonist of the farnesoid X receptor (FXR) with an IC50 of 0.89 μM. This compound exhibits notable activity in modulating intestinal FXR signaling pathways, making it valuable for research related to metabolic disease and bile acid regulation. It serves as a useful tool in studying the physiological roles of FXR in gastrointestinal disorders and potential therapeutic interventions.
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