Product Data Sheet

UDP-GalNAz disodium

Catalog No. A75027

main product photo
UDP-GalNAz disodium is an analogue of UDP-GalNAc disodium, serving as a donor substrate for N-acetylgalactosaminyltransferases, which facilitate the transfer of GalNAc to various saccharide or peptide acceptors. This compound features an azide group, making it a valuable reagent for click chemistry applications. UDP-GalNAz disodium can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. It is useful in the study of glycosylation pathways and the synthesis of complex glycoproteins.
Chemical Information
Catalog NumA75027
M. Wt692.33
FormulaC17H24N6Na2O17P2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.653600-61-4
SynonymsUDP-N-azidoacetylgalactosamine disodium
SMILESO[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(O[C@@H]3[C@H](NC(CN=[N+]=[N-])=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O[Na])=O)(O[Na])=O
Biological Activity
DescriptionUDP-GalNAz disodium is an analogue of UDP-GalNAc disodium, serving as a donor substrate for N-acetylgalactosaminyltransferases, which facilitate the transfer of GalNAc to various saccharide or peptide acceptors. This compound features an azide group, making it a valuable reagent for click chemistry applications. UDP-GalNAz disodium can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions involving DBCO or BCN groups. It is useful in the study of glycosylation pathways and the synthesis of complex glycoproteins.
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SHIPPING AND STORAGE
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