Product Data Sheet
NCGC00092410
Catalog No. A75069
NCGC00092410 is a selective glucocerebrosidase chaperone that enhances the enzyme's activity and lysosomal localization in mutant cell lines. With an IC50 of 31 nM, it demonstrates notable potency without affecting related hydrolases at concentrations up to 77 μM. This reagent is primarily utilized in research focused on Gaucher disease, providing insights into therapeutic strategies for this lysosomal storage disorder.
Chemical Information
| Catalog Num | A75069 |
|---|---|
| M. Wt | 353.46 |
| Formula | C21H27N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 442898-34-2 |
| Synonyms | |
| SMILES | O=C(C1CCCCC1)NC2=CC=C3N=C(N4CCOCC4)C=C(C)C3=C2 |
Biological Activity
| Description | NCGC00092410 is a selective glucocerebrosidase chaperone that enhances the enzyme's activity and lysosomal localization in mutant cell lines. With an IC50 of 31 nM, it demonstrates notable potency without affecting related hydrolases at concentrations up to 77 μM. This reagent is primarily utilized in research focused on Gaucher disease, providing insights into therapeutic strategies for this lysosomal storage disorder. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
