Product Data Sheet

α-Glucosidase-IN-36

Catalog No. A75198

main product photo
α-Glucosidase-IN-36 is a selective inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and Ki and Kis values of 1.65 μM and 4.54 μM, respectively. This compound functions by binding to the active site of α-glucosidase, leading to alterations in its secondary structure, which subsequently inhibits enzyme activity. α-Glucosidase-IN-36 is valuable for research applications related to type 2 diabetes mellitus (T2DM), enabling investigations into carbohydrate metabolism and glycemic control.
Chemical Information
Catalog NumA75198
M. Wt566.47
FormulaC26H24BrN5O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3025234-94-7
Synonyms
SMILESBrC1=CC=C(/C=N/N2C(COC3=CC=CC=C3)=NN=C2SCC(NC4=CC=C(OCC)C=C4)=O)C=C1
Biological Activity
Descriptionα-Glucosidase-IN-36 is a selective inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and Ki and Kis values of 1.65 μM and 4.54 μM, respectively. This compound functions by binding to the active site of α-glucosidase, leading to alterations in its secondary structure, which subsequently inhibits enzyme activity. α-Glucosidase-IN-36 is valuable for research applications related to type 2 diabetes mellitus (T2DM), enabling investigations into carbohydrate metabolism and glycemic control.
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