Product Data Sheet

Zn(II) Mesoporphyrin IX

Catalog No. A75264

main product photo
Zn(II) Mesoporphyrin IX is a potent inhibitor of heme oxygenase, particularly affecting the enzymatic activity in bone marrow. This compound demonstrates significant biological activity by inhibiting the growth of erythroid and myeloid progenitor cells, as well as blocking rhG-CSF-induced mobilization of these cells into peripheral blood. Zn(II) Mesoporphyrin IX is suitable for research applications involving hematopoietic regulation. However, its photochemical properties and potential toxicity to hematopoietic growth warrant careful consideration in experimental designs.
Chemical Information
Catalog NumA75264
M. Wt630.05
FormulaC34H36N4O4Zn
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.14354-67-7
SynonymsZnMP
SMILESO=C(CCC1=C(C)C2=CC3=C(C)C(CC)=C4C=C5C(C)=C(CC)C6=[N]5[Zn+2]([N-]34)([N-]78)[N]2=C1C=C8C(CCC(O)=O)=C(C)C7=C6)O
Biological Activity
DescriptionZn(II) Mesoporphyrin IX is a potent inhibitor of heme oxygenase, particularly affecting the enzymatic activity in bone marrow. This compound demonstrates significant biological activity by inhibiting the growth of erythroid and myeloid progenitor cells, as well as blocking rhG-CSF-induced mobilization of these cells into peripheral blood. Zn(II) Mesoporphyrin IX is suitable for research applications involving hematopoietic regulation. However, its photochemical properties and potential toxicity to hematopoietic growth warrant careful consideration in experimental designs.
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SHIPPING AND STORAGE
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