Product Data Sheet

Mn(III) Protoporphyrin IX chloride

Catalog No. A75268

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Mn(III) Protoporphyrin IX Chloride is a potent inducer of heme oxygenase (HO) that enhances the expression of δ-aminolevulinate synthase and HO genes in chick embryo liver cells at a concentration of 10 μM. This metalloporphyrin is relevant for studying heme biosynthesis and degradation pathways. Additionally, Mn(III) protoporphyrin IX chloride has been utilized in the development of nanobialys for magnetic resonance imaging (MRI) of fibrin clots in vitro, as well as in the synthesis of metalloporphyrin conjugates with microperoxidase activity, further expanding its applications in chemical research.
Chemical Information
Catalog NumA75268
M. Wt651.03
FormulaC34H32ClMnN4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.120389-54-0
SynonymsManganese(III) Protoporphyrin IX Chloride
SMILESO=C(CCC1=C(C)C2=[N]3C1=CC4=C(CCC([O-])=O)C(C)=C5C=C6C(C=C)=C(C)C(C=C7C(C=C)=C(C)C8=C2)=[N]6[Mn+3]3([N-]78)([N-]54)[Cl-])[O-].[H+].[H+]
Biological Activity
DescriptionMn(III) Protoporphyrin IX Chloride is a potent inducer of heme oxygenase (HO) that enhances the expression of δ-aminolevulinate synthase and HO genes in chick embryo liver cells at a concentration of 10 μM. This metalloporphyrin is relevant for studying heme biosynthesis and degradation pathways. Additionally, Mn(III) protoporphyrin IX chloride has been utilized in the development of nanobialys for magnetic resonance imaging (MRI) of fibrin clots in vitro, as well as in the synthesis of metalloporphyrin conjugates with microperoxidase activity, further expanding its applications in chemical research.
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