Product Data Sheet
HIF-PHD-IN-1
Catalog No. A75564
HIF-PHD-IN-1 is a potent inhibitor of hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), demonstrating an IC50 of 54 nM specifically for human HIF-PHD2. This compound exhibits significant biological activity by stabilizing hypoxia-inducible factors, thereby enhancing erythropoiesis. HIF-PHD-IN-1 holds potential for research applications in renal anemia therapy and related studies exploring oxygen-sensing pathways.
Chemical Information
| Catalog Num | A75564 |
|---|---|
| M. Wt | 419.22 |
| Formula | C17H12Cl2N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1567657-46-8 |
| Synonyms | |
| SMILES | O=C(C1=CN(C2=NC3=C(N([C@H](C4=CC(Cl)=CC=C4Cl)C)N=C3)C(N2)=O)N=C1)O |
Biological Activity
| Description | HIF-PHD-IN-1 is a potent inhibitor of hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), demonstrating an IC50 of 54 nM specifically for human HIF-PHD2. This compound exhibits significant biological activity by stabilizing hypoxia-inducible factors, thereby enhancing erythropoiesis. HIF-PHD-IN-1 holds potential for research applications in renal anemia therapy and related studies exploring oxygen-sensing pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
