Product Data Sheet
Enarodustat hydrochloride
Catalog No. A75574
Enarodustat hydrochloride is a potent inhibitor of hypoxia-inducible factor (HIF) and HIF prolyl-hydroxylase, exhibiting an EC50 of 0.22 μM. This compound is primarily investigated for its potential in the treatment of renal anemia by stabilizing HIF, thereby promoting erythropoiesis and improving oxygenation in tissues. It serves as a valuable tool for research in hypoxia-related pathways and anemia therapies.
Chemical Information
| Catalog Num | A75574 |
|---|---|
| M. Wt | 376.79 |
| Formula | C17H17ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1262131-60-1 |
| Synonyms | JTZ-951 hydrochloride; SAL0951 hydrochloride |
| SMILES | O=C(C(C1=NC=NN1C(CCC2=CC=CC=C2)=C3)=C3O)NCC(O)=O.Cl |
Biological Activity
| Description | Enarodustat hydrochloride is a potent inhibitor of hypoxia-inducible factor (HIF) and HIF prolyl-hydroxylase, exhibiting an EC50 of 0.22 μM. This compound is primarily investigated for its potential in the treatment of renal anemia by stabilizing HIF, thereby promoting erythropoiesis and improving oxygenation in tissues. It serves as a valuable tool for research in hypoxia-related pathways and anemia therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
