Product Data Sheet
Izilendustat hydrochloride
Catalog No. A75575
Izilendustat hydrochloride is a potent prolyl hydroxylase inhibitor that stabilizes hypoxia-inducible factors, specifically HIF-1α and HIF-2. This compound exhibits significant biological activity by enhancing cellular responses to hypoxia, making it a valuable tool for investigating diseases related to HIF-1α, such as peripheral vascular disease, coronary artery disease, heart failure, ischemia, anemia, and inflammatory bowel diseases. Izilendustat hydrochloride is instrumental in research exploring therapeutic strategies targeting hypoxic conditions.
Chemical Information
| Catalog Num | A75575 |
|---|---|
| M. Wt | 470.39 |
| Formula | C22H29Cl2N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1303513-80-5 |
| Synonyms | |
| SMILES | O=C(N1CCN(CC(C=CN2CC3=CC=C(Cl)C=C3)=C(O)C2=O)CC1)OC(C)(C)C.[H]Cl |
Biological Activity
| Description | Izilendustat hydrochloride is a potent prolyl hydroxylase inhibitor that stabilizes hypoxia-inducible factors, specifically HIF-1α and HIF-2. This compound exhibits significant biological activity by enhancing cellular responses to hypoxia, making it a valuable tool for investigating diseases related to HIF-1α, such as peripheral vascular disease, coronary artery disease, heart failure, ischemia, anemia, and inflammatory bowel diseases. Izilendustat hydrochloride is instrumental in research exploring therapeutic strategies targeting hypoxic conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
