Product Data Sheet

RH01504

Catalog No. A75578

main product photo
RH01504 is a potent inhibitor of HIF2α, exhibiting a Kd value of 5.42 nM against human HIF2α. This compound effectively suppresses the proliferation of renal cancer cells, making it a valuable tool for investigating renal cell carcinoma. RH01504 is applicable in research exploring the molecular mechanisms underlying hypoxia-driven tumor progression and offers potential insights into therapeutic strategies targeting HIF2α in cancer treatments.
Chemical Information
Catalog NumA75578
M. Wt277.70
FormulaC14H12ClNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.301335-35-3
Synonyms
SMILESCOC1=CC(C(C2=C(C=CC(Cl)=C2)N)=O)=CC=C1O
Biological Activity
DescriptionRH01504 is a potent inhibitor of HIF2α, exhibiting a Kd value of 5.42 nM against human HIF2α. This compound effectively suppresses the proliferation of renal cancer cells, making it a valuable tool for investigating renal cell carcinoma. RH01504 is applicable in research exploring the molecular mechanisms underlying hypoxia-driven tumor progression and offers potential insights into therapeutic strategies targeting HIF2α in cancer treatments.
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