Product Data Sheet
OHM1
Catalog No. A75607
OHM1 is an analog of the HIF1α C-terminal transactivation domain (CTAD) that selectively inhibits the interaction between HIF1α and the coactivators p300/CBP. With an affinity of 0.53 μM for the CH1 domain, OHM1 effectively disrupts HIF1α-mediated transcriptional activity. This compound is valuable for research applications focused on hypoxia signaling, cancer biology, and the regulation of cellular responses to oxygen levels.
Chemical Information
| Catalog Num | A75607 |
|---|---|
| M. Wt | 494.63 |
| Formula | C24H42N6O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1450995-09-1 |
| Synonyms | |
| SMILES | O=C(N)[C@@H](N1C([C@H](C)N(C([C@@H](N2C([C@H](CC(C)C)NCC2)=O)CC(C)C)=O)CC1)=O)CCC(N)=O |
Biological Activity
| Description | OHM1 is an analog of the HIF1α C-terminal transactivation domain (CTAD) that selectively inhibits the interaction between HIF1α and the coactivators p300/CBP. With an affinity of 0.53 μM for the CH1 domain, OHM1 effectively disrupts HIF1α-mediated transcriptional activity. This compound is valuable for research applications focused on hypoxia signaling, cancer biology, and the regulation of cellular responses to oxygen levels. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
