Product Data Sheet
DS79540454
Catalog No. A75611
DS79540454 is a selective inhibitor of hypoxia-inducible factor prolyl hydroxylase domain 2 (HIF-PHD2) with an IC50 of 0.26 μM. This compound plays a crucial role in regulating cellular responses to hypoxia by stabilizing hypoxia-inducible factor (HIF) levels. DS79540454 is primarily utilized in studies related to renal anemia and offers insights into the therapeutic modulation of erythropoiesis under hypoxic conditions.
Chemical Information
| Catalog Num | A75611 |
|---|---|
| M. Wt | 420.42 |
| Formula | C22H20N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1462947-17-6 |
| Synonyms | |
| SMILES | O=C(C1=CN=C(NC(CCC(O)=O)=O)N=C1O)NCC2=CC(C3=CC=CC=C3)=CC=C2 |
Biological Activity
| Description | DS79540454 is a selective inhibitor of hypoxia-inducible factor prolyl hydroxylase domain 2 (HIF-PHD2) with an IC50 of 0.26 μM. This compound plays a crucial role in regulating cellular responses to hypoxia by stabilizing hypoxia-inducible factor (HIF) levels. DS79540454 is primarily utilized in studies related to renal anemia and offers insights into the therapeutic modulation of erythropoiesis under hypoxic conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
