Product Data Sheet
CLB-016
Catalog No. A75624
CLB-016 is a potent inhibitor of Hypoxia-inducible factor 1 (HIF-1) with an IC50 of 19.1 µM. This compound effectively suppresses HIF-1-mediated responses to hypoxia, making it a valuable tool for research focused on cellular adaptation to low oxygen conditions. CLB-016 is applicable in studies examining the role of HIF in tumor progression, metabolic regulation, and other hypoxia-related pathologies.
Chemical Information
| Catalog Num | A75624 |
|---|---|
| M. Wt | 356.38 |
| Formula | C17H20N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1005636-29-2 |
| Synonyms | |
| SMILES | O=C(C1=NN(CC)C=C1NC(C2=CC=C(CN3N=C(C)C=C3C)O2)=O)N |
Biological Activity
| Description | CLB-016 is a potent inhibitor of Hypoxia-inducible factor 1 (HIF-1) with an IC50 of 19.1 µM. This compound effectively suppresses HIF-1-mediated responses to hypoxia, making it a valuable tool for research focused on cellular adaptation to low oxygen conditions. CLB-016 is applicable in studies examining the role of HIF in tumor progression, metabolic regulation, and other hypoxia-related pathologies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
