Product Data Sheet

BMS-986242

Catalog No. A75725

main product photo
BMS-986242 is a selective, orally active inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1). This compound demonstrates potent inhibition of IDO1 enzymatic activity, a critical pathway in the immunosuppressive tumor microenvironment. Research applications include exploring its use in combination therapies for cancer treatment and investigating its effects on immune response modulation.
Chemical Information
Catalog NumA75725
M. Wt410.91
FormulaC24H24ClFN2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1923844-48-7
Synonyms
SMILESFC1=CC2=C(C=C1)N=CC=C2[C@H]3CC[C@@](CC3)([H])[C@@H](C)NC(C4=CC=C(C=C4)Cl)=O
Biological Activity
DescriptionBMS-986242 is a selective, orally active inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1). This compound demonstrates potent inhibition of IDO1 enzymatic activity, a critical pathway in the immunosuppressive tumor microenvironment. Research applications include exploring its use in combination therapies for cancer treatment and investigating its effects on immune response modulation.
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