Product Data Sheet

(Rac)-LY-3381916

Catalog No. A75730

main product photo
(Rac)-LY-3381916 is a potent inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1), specifically targeting its apo- form. This racemic compound demonstrates selective inhibition of IDO1 activity and is capable of penetrating the blood-brain barrier. Its unique mechanism of action makes it valuable for research applications focused on immunotherapy and neurological diseases where modulation of the kynurenine pathway is critical.
Chemical Information
Catalog NumA75730
M. Wt396.45
FormulaC23H25FN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2166616-74-4
Synonyms(Rac)-IDO1-IN-5
SMILESO=C(NC(C1=CC2=C(N(C(C3CCOCC3)=O)CC2)C=C1)C)C4=CC=C(F)C=C4
Biological Activity
Description(Rac)-LY-3381916 is a potent inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1), specifically targeting its apo- form. This racemic compound demonstrates selective inhibition of IDO1 activity and is capable of penetrating the blood-brain barrier. Its unique mechanism of action makes it valuable for research applications focused on immunotherapy and neurological diseases where modulation of the kynurenine pathway is critical.
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SHIPPING AND STORAGE
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