Product Data Sheet
IDO1-IN-16
Catalog No. A75769
IDO1-IN-16 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), demonstrating an IC50 of 127 nM against the holoenzyme. This compound is essential for research applications in immunology, particularly in studying tumor microenvironments and modulating immune responses. IDO1-IN-16 can aid in the development of novel therapeutic strategies for cancer and autoimmune diseases by inhibiting the enzymatic activity that leads to immune tolerance.
Chemical Information
| Catalog Num | A75769 |
|---|---|
| M. Wt | 536.48 |
| Formula | C25H35BrFN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2677054-63-4 |
| Synonyms | |
| SMILES | O=C(NCCC)NC1=CC(/C(NO)=N\C2=CC=C(C(Br)=C2)F)=CC=C1N(CC(C)C)CC(C)C |
Biological Activity
| Description | IDO1-IN-16 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), demonstrating an IC50 of 127 nM against the holoenzyme. This compound is essential for research applications in immunology, particularly in studying tumor microenvironments and modulating immune responses. IDO1-IN-16 can aid in the development of novel therapeutic strategies for cancer and autoimmune diseases by inhibiting the enzymatic activity that leads to immune tolerance. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
