Product Data Sheet
IDH1 Inhibitor 5
Catalog No. A75799
IDH1 Inhibitor 5 is an inhibitor of isocitrate dehydrogenase 1 (IDH1), targeting both wild-type and mutant forms of the enzyme. It demonstrates potent biological activity with IC50 values of 64.4 nM in MOG cells and 34.9 nM in glioma cells expressing the exogenous mutant IDH1 R132H protein. This compound is valuable for research applications focused on glioma and other IDH1-related oncogenic processes.
Chemical Information
| Catalog Num | A75799 |
|---|---|
| M. Wt | 450.57 |
| Formula | C26H34N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1940128-37-9 |
| Synonyms | |
| SMILES | CC(O[C@H]1CC[C@@H](CC1)C(N2CC3=C(NC4=C2C=C(C=C4)N5CCOCC5)N=CC=C3)=O)C |
Biological Activity
| Description | IDH1 Inhibitor 5 is an inhibitor of isocitrate dehydrogenase 1 (IDH1), targeting both wild-type and mutant forms of the enzyme. It demonstrates potent biological activity with IC50 values of 64.4 nM in MOG cells and 34.9 nM in glioma cells expressing the exogenous mutant IDH1 R132H protein. This compound is valuable for research applications focused on glioma and other IDH1-related oncogenic processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
