Product Data Sheet
GSK990
Catalog No. A75807
GSK990 is an inactive mutant isocitrate dehydrogenase 1 (IDH1) inhibitor that exhibits no significant inhibitory activity against either wild-type or mutant IDH1/IDH2 enzymes. This compound is primarily utilized as a negative control in research studies involving the active IDH1 inhibitor GSK321. GSK990 is particularly relevant for investigations focusing on acute myeloid leukemia, enabling researchers to validate the specificity and efficacy of IDH1-targeted treatments.
Chemical Information
| Catalog Num | A75807 |
|---|---|
| M. Wt | 429.47 |
| Formula | C23H23N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1816331-64-2 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CC(C)=C1)C2=NN(C3=C2CN(CC3)C(C4=CC=CN4)=O)CC5=CNC=N5 |
Biological Activity
| Description | GSK990 is an inactive mutant isocitrate dehydrogenase 1 (IDH1) inhibitor that exhibits no significant inhibitory activity against either wild-type or mutant IDH1/IDH2 enzymes. This compound is primarily utilized as a negative control in research studies involving the active IDH1 inhibitor GSK321. GSK990 is particularly relevant for investigations focusing on acute myeloid leukemia, enabling researchers to validate the specificity and efficacy of IDH1-targeted treatments. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
