Product Data Sheet
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium
Catalog No. A76269
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a phospholipid compound targeting liposome formation. It plays a crucial role in the construction of vesicles composed of concentric phospholipid bilayer membranes, serving as effective platforms for drug delivery systems, particularly in oncological and antimicrobial applications. This compound facilitates the encapsulation of highly polar water-soluble agents within the internal aqueous space of liposomes, while lipophilic compounds integrate into the lipid bilayer. Its use is especially advantageous for the delivery of antisense oligonucleotides, addressing challenges related to cellular uptake efficiency and systemic stability.
Chemical Information
| Catalog Num | A76269 |
|---|---|
| M. Wt | 805.99 |
| Formula | C42H73NNaO10P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 321883-39-0 |
| Synonyms | 18:2 PS sodium |
| SMILES | O=C(O[Na])[C@@H](N)COP(OC[C@@H](COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(O)=O |
Biological Activity
| Description | 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a phospholipid compound targeting liposome formation. It plays a crucial role in the construction of vesicles composed of concentric phospholipid bilayer membranes, serving as effective platforms for drug delivery systems, particularly in oncological and antimicrobial applications. This compound facilitates the encapsulation of highly polar water-soluble agents within the internal aqueous space of liposomes, while lipophilic compounds integrate into the lipid bilayer. Its use is especially advantageous for the delivery of antisense oligonucleotides, addressing challenges related to cellular uptake efficiency and systemic stability. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
