Product Data Sheet
BW B70C
Catalog No. A76442
BW B70C is a potent and selective inhibitor of arachidonic acid 5-lipoxygenase, demonstrating oral bioactivity. It effectively inhibits both acute and allergic bronchoconstriction, as well as late-phase eosinophil accumulation following allergen exposure in guinea pigs. BW B70C prevents the synthesis of leukotriene C4 and modulates leukocyte migration to the airway lumen, along with reducing albumin microvascular leakage. This compound holds promise for research into anti-asthmatic agents and related inflammatory conditions.
Chemical Information
| Catalog Num | A76442 |
|---|---|
| M. Wt | 316.33 |
| Formula | C17H17FN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 134470-38-5 |
| Synonyms | |
| SMILES | O=C(N)N(C(C)/C=C/C1=CC=CC(OC2=CC=C(F)C=C2)=C1)O |
Biological Activity
| Description | BW B70C is a potent and selective inhibitor of arachidonic acid 5-lipoxygenase, demonstrating oral bioactivity. It effectively inhibits both acute and allergic bronchoconstriction, as well as late-phase eosinophil accumulation following allergen exposure in guinea pigs. BW B70C prevents the synthesis of leukotriene C4 and modulates leukocyte migration to the airway lumen, along with reducing albumin microvascular leakage. This compound holds promise for research into anti-asthmatic agents and related inflammatory conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
