Product Data Sheet
(±)15-HEDE
Catalog No. A76445
(±)15-HEDE is a racemic mixture comprised of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE, derived from eicosadienoic acid within macrophages. This compound acts as a selective inhibitor of 5-lipoxygenase (5-LO) with an IC50 value of 35 μM. 15-HEDE is utilized in research to investigate lipoxygenase pathways and their implications in inflammatory processes. Its inhibitory effects on 5-LO make it a valuable tool for studying the modulation of leukotriene biosynthesis and related biological activities.
Chemical Information
| Catalog Num | A76445 |
|---|---|
| M. Wt | 324.50 |
| Formula | C20H36O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 77159-57-0 |
| Synonyms | |
| SMILES | CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O |
Biological Activity
| Description | (±)15-HEDE is a racemic mixture comprised of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE, derived from eicosadienoic acid within macrophages. This compound acts as a selective inhibitor of 5-lipoxygenase (5-LO) with an IC50 value of 35 μM. 15-HEDE is utilized in research to investigate lipoxygenase pathways and their implications in inflammatory processes. Its inhibitory effects on 5-LO make it a valuable tool for studying the modulation of leukotriene biosynthesis and related biological activities. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
