Product Data Sheet
AA863
Catalog No. A76468
AA863 is a selective inhibitor of 5-lipoxygenase, which plays a crucial role in the metabolism of arachidonic acid and the production of leukotrienes. This compound demonstrates significant dose-dependent inhibition of human glioma cell proliferation, with an IC50 value of 9.0 micromolar in monolayer cultures. AA863 is a valuable tool for researchers investigating glioma biology and the therapeutic potential of targeting lipoxygenase pathways.
Chemical Information
| Catalog Num | A76468 |
|---|---|
| M. Wt | 358.43 |
| Formula | C21H26O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 80809-95-6 |
| Synonyms | |
| SMILES | O=C1C(CCCCC#CCCCC#CCO)=C(C(C(OC)=C1OC)=O)C |
Biological Activity
| Description | AA863 is a selective inhibitor of 5-lipoxygenase, which plays a crucial role in the metabolism of arachidonic acid and the production of leukotrienes. This compound demonstrates significant dose-dependent inhibition of human glioma cell proliferation, with an IC50 value of 9.0 micromolar in monolayer cultures. AA863 is a valuable tool for researchers investigating glioma biology and the therapeutic potential of targeting lipoxygenase pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
