Product Data Sheet

LP117

Catalog No. A76509

main product photo
LP117 is a potent inhibitor of 5-Lipoxygenase (5-LO), demonstrating an IC50 value of 1.1 μM. This compound impedes the synthesis of 5-LO products, thereby regulating inflammatory pathways. LP117 is applicable in research focused on inflammatory diseases, asthma, and other conditions influenced by leukotriene metabolism. Its selectivity and efficacy make it a valuable tool for studying lipoxygenase-related mechanisms in biological systems.
Chemical Information
Catalog NumA76509
M. Wt430.95
FormulaC21H23ClN4O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1056468-55-3
Synonyms
SMILESCCCCC(SC1=NC(NC2=CC=C3N=CC=CC3=C2)=CC(Cl)=N1)C(OCC)=O
Biological Activity
DescriptionLP117 is a potent inhibitor of 5-Lipoxygenase (5-LO), demonstrating an IC50 value of 1.1 μM. This compound impedes the synthesis of 5-LO products, thereby regulating inflammatory pathways. LP117 is applicable in research focused on inflammatory diseases, asthma, and other conditions influenced by leukotriene metabolism. Its selectivity and efficacy make it a valuable tool for studying lipoxygenase-related mechanisms in biological systems.
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