Product Data Sheet
Lagunamycin
Catalog No. A76510
Lagunamycin is a selective inhibitor of 5-lipoxygenase, derived from the culture medium of Streptomyces sp. AA0310. It demonstrates significant inhibitory activity with an IC50 value of 6.08 μM against rat 5-lipoxygenase, effectively preventing leukotriene biosynthesis. Notably, lagunamycin achieves this inhibition without inducing lipid peroxidation, making it a valuable tool for studying inflammatory processes and potential therapeutic applications in conditions mediated by 5-lipoxygenase activity.
Chemical Information
| Catalog Num | A76510 |
|---|---|
| M. Wt | 355.39 |
| Formula | C19H21N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 150693-65-5 |
| Synonyms | |
| SMILES | O=C1NC2=C(C(C(C(C2=O)=O)=[N+]=[N-])=O)C(/C(C)=C/[C@H](C)CC(C)C)=C1C |
Biological Activity
| Description | Lagunamycin is a selective inhibitor of 5-lipoxygenase, derived from the culture medium of Streptomyces sp. AA0310. It demonstrates significant inhibitory activity with an IC50 value of 6.08 μM against rat 5-lipoxygenase, effectively preventing leukotriene biosynthesis. Notably, lagunamycin achieves this inhibition without inducing lipid peroxidation, making it a valuable tool for studying inflammatory processes and potential therapeutic applications in conditions mediated by 5-lipoxygenase activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
