Product Data Sheet
CMI-392
Catalog No. A76516
CMI-392 is a dual inhibitor of 5-lipoxygenase and a platelet-activating factor (PAF) receptor antagonist, exhibiting IC50 values of 100 nM and 10 nM, respectively. This compound demonstrates significant anti-inflammatory activities by modulating leukotriene synthesis and PAF signaling pathways. CMI-392 is valuable for research applications focused on inflammatory diseases and related therapeutic targets.
Chemical Information
| Catalog Num | A76516 |
|---|---|
| M. Wt | 633.15 |
| Formula | C31H37ClN2O8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 193739-23-0 |
| Synonyms | LDP-392 |
| SMILES | O=C(NCC1=CC([C@H]2O[C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC2)=CC(OC)=C1OCCSC4=CC=C(Cl)C=C4)N(O)C |
Biological Activity
| Description | CMI-392 is a dual inhibitor of 5-lipoxygenase and a platelet-activating factor (PAF) receptor antagonist, exhibiting IC50 values of 100 nM and 10 nM, respectively. This compound demonstrates significant anti-inflammatory activities by modulating leukotriene synthesis and PAF signaling pathways. CMI-392 is valuable for research applications focused on inflammatory diseases and related therapeutic targets. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
