Product Data Sheet
Finerenone-d3
Catalog No. A76659
Finerenone-d3 is a deuterium-labeled form of finerenone, a selective, orally active nonsteroidal mineralocorticoid receptor (MR) antagonist with an IC50 of 18 nM. This compound exhibits remarkable selectivity against glucocorticoid, androgen, and progesterone receptors, with over 500-fold selectivity. Finerenone-d3 is valuable for studying cardiorenal diseases, including type 2 diabetes mellitus and chronic kidney disease, enabling detailed metabolic and pharmacokinetic investigations in research settings.
Chemical Information
| Catalog Num | A76659 |
|---|---|
| M. Wt | 381.44 |
| Formula | C21H19D3N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2917530-37-9 |
| Synonyms | BAY 94-8862-d3 |
| SMILES | O=C(C1=C(C)NC2=C(C(OCC)=NC=C2C)[C@@H]1C3=CC=C(C#N)C=C3OC([2H])([2H])[2H])N |
Biological Activity
| Description | Finerenone-d3 is a deuterium-labeled form of finerenone, a selective, orally active nonsteroidal mineralocorticoid receptor (MR) antagonist with an IC50 of 18 nM. This compound exhibits remarkable selectivity against glucocorticoid, androgen, and progesterone receptors, with over 500-fold selectivity. Finerenone-d3 is valuable for studying cardiorenal diseases, including type 2 diabetes mellitus and chronic kidney disease, enabling detailed metabolic and pharmacokinetic investigations in research settings. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
