Product Data Sheet
MPP+-d3 iodide
Catalog No. A76714
MPP+-d3 iodide is a deuterium-labeled derivative of MPP+ (iodide), primarily targeting dopaminergic neurons. This compound is known for inducing Parkinson’s disease-like symptoms in animal models by selectively damaging dopaminergic neurons in the substantia nigra, primarily through its action on mitochondrial complex I within the respiratory chain. Additionally, MPP+ iodide serves as a high-affinity substrate for the serotonin transporter (SERT), making it useful for studies examining the neurotoxic mechanisms and transport processes in neurodegenerative disease research.
Chemical Information
| Catalog Num | A76714 |
|---|---|
| M. Wt | 300.15 |
| Formula | C12H9D3IN |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 207556-07-8 |
| Synonyms | |
| SMILES | [2H]C([2H])([2H])[N+]1=CC=C(C2=CC=CC=C2)C=C1.[I-] |
Biological Activity
| Description | MPP+-d3 iodide is a deuterium-labeled derivative of MPP+ (iodide), primarily targeting dopaminergic neurons. This compound is known for inducing Parkinson’s disease-like symptoms in animal models by selectively damaging dopaminergic neurons in the substantia nigra, primarily through its action on mitochondrial complex I within the respiratory chain. Additionally, MPP+ iodide serves as a high-affinity substrate for the serotonin transporter (SERT), making it useful for studies examining the neurotoxic mechanisms and transport processes in neurodegenerative disease research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
