Product Data Sheet

NOX2-IN-1

Catalog No. A76922

main product photo
NOX2-IN-1 is a selective inhibitor of nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2). It effectively disrupts the protein-protein interaction between p47phox and p22phox, demonstrating favorable binding affinities and significant cellular activity. This compound is valuable for research applications focusing on oxidative stress-related diseases and inflammation pathways.
Chemical Information
Catalog NumA76922
M. Wt390.44
FormulaC22H22N4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2648709-25-3
Synonyms
SMILESNC1=NC2=CC=CC(OCCOCCOC3=C4C=CC(N)=NC4=CC=C3)=C2C=C1
Biological Activity
DescriptionNOX2-IN-1 is a selective inhibitor of nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2). It effectively disrupts the protein-protein interaction between p47phox and p22phox, demonstrating favorable binding affinities and significant cellular activity. This compound is valuable for research applications focusing on oxidative stress-related diseases and inflammation pathways.
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SHIPPING AND STORAGE
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