Product Data Sheet
Sacubitril sodium
Catalog No. A76952
Sacubitril sodium is a potent and orally active neprilysin (NEP) inhibitor, exhibiting an IC50 of 5 nM. By enhancing the activity of the natriuretic peptide (NP) system, it demonstrates significant antihypertensive effects. Sacubitril sodium is not only crucial in heart failure therapy but also serves as a valuable tool for research related to heart failure, hypertension, and COVID-19.
Chemical Information
| Catalog Num | A76952 |
|---|---|
| M. Wt | 433.47 |
| Formula | C24H28NNaO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 149690-05-1 |
| Synonyms | AHU-377 sodium |
| SMILES | O=C(CCC(O[Na])=O)N[C@H](CC1=CC=C(C2=CC=CC=C2)C=C1)C[C@@H](C)C(OCC)=O |
Biological Activity
| Description | Sacubitril sodium is a potent and orally active neprilysin (NEP) inhibitor, exhibiting an IC50 of 5 nM. By enhancing the activity of the natriuretic peptide (NP) system, it demonstrates significant antihypertensive effects. Sacubitril sodium is not only crucial in heart failure therapy but also serves as a valuable tool for research related to heart failure, hypertension, and COVID-19. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
