Product Data Sheet
NEP28
Catalog No. A76966
NEP28 is a selective androgen receptor modulator with a reported EC50 of 2.90 nM in 22RV1 cells. It enhances the activity of the Aβ-degrading enzyme neprilysin, demonstrating potential therapeutic benefits in muscle and brain tissue while mitigating adverse effects in the prostate as observed in rat models. This compound is suitable for research applications targeting osteoporosis, sarcopenia, and Alzheimer's disease.
Chemical Information
| Catalog Num | A76966 |
|---|---|
| M. Wt | 327.16 |
| Formula | C10H10BrF3N2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1254176-87-8 |
| Synonyms | |
| SMILES | N#CC=1SC(=CC1Br)N(CCC)CC(F)(F)F |
Biological Activity
| Description | NEP28 is a selective androgen receptor modulator with a reported EC50 of 2.90 nM in 22RV1 cells. It enhances the activity of the Aβ-degrading enzyme neprilysin, demonstrating potential therapeutic benefits in muscle and brain tissue while mitigating adverse effects in the prostate as observed in rat models. This compound is suitable for research applications targeting osteoporosis, sarcopenia, and Alzheimer's disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
