Product Data Sheet
KH064
Catalog No. A77112
KH064 is a potent inhibitor of secretory phospholipase A2 (sPLA2), specifically targeting human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa) with an IC50 of 29 nM. This D-tyrosine derivative exhibits significant anti-inflammatory activity, making it suitable for research applications in inflammation and related disease models. Its oral bioavailability further enhances its potential for in vivo studies in pharmacological and toxicological research.
Chemical Information
| Catalog Num | A77112 |
|---|---|
| M. Wt | 487.63 |
| Formula | C31H37NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 393569-31-8 |
| Synonyms | |
| SMILES | OC(CC[C@@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC(CCCCCCC3=CC=CC=C3)=O)=O |
Biological Activity
| Description | KH064 is a potent inhibitor of secretory phospholipase A2 (sPLA2), specifically targeting human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa) with an IC50 of 29 nM. This D-tyrosine derivative exhibits significant anti-inflammatory activity, making it suitable for research applications in inflammation and related disease models. Its oral bioavailability further enhances its potential for in vivo studies in pharmacological and toxicological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
