Product Data Sheet
LY-311727
Catalog No. A77128
LY-311727 is a potent inhibitor of secretory non-pancreatic phospholipase A2 (sPLA2), demonstrating an IC50 of less than 1 μM for group IIA sPLA2. This compound functions by blocking the enzymatic activity of sPLA2, which plays a critical role in proinflammatory processes. LY-311727 is valuable for research focused on the modulation of inflammation and the investigation of sPLA2-related biological pathways.
Chemical Information
| Catalog Num | A77128 |
|---|---|
| M. Wt | 430.43 |
| Formula | C22H27N2O5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 164083-84-5 |
| Synonyms | |
| SMILES | NC(CC1=C(CC)N(CC2=CC=CC=C2)C3=C1C=C(OCCCP(O)(O)=O)C=C3)=O |
Biological Activity
| Description | LY-311727 is a potent inhibitor of secretory non-pancreatic phospholipase A2 (sPLA2), demonstrating an IC50 of less than 1 μM for group IIA sPLA2. This compound functions by blocking the enzymatic activity of sPLA2, which plays a critical role in proinflammatory processes. LY-311727 is valuable for research focused on the modulation of inflammation and the investigation of sPLA2-related biological pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
