Product Data Sheet

(S)-Bromoenol lactone

Catalog No. A77129

main product photo
(S)-Bromoenol lactone is an irreversible inhibitor targeting calcium-independent phospholipase A2β (iPLA2β). It effectively reduces the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells, demonstrating an IC50 of 2 µM. This compound serves as a valuable tool for studying phospholipase activity and its role in various cellular processes.
Chemical Information
Catalog NumA77129
M. Wt317.18
FormulaC16H13BrO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.478288-94-7
Synonyms(S)-BEL; (S,E)-Bromoenol lactone
SMILESO=C1[C@H](C2=C3C=CC=CC3=CC=C2)CC/C(O1)=C\Br
Biological Activity
Description(S)-Bromoenol lactone is an irreversible inhibitor targeting calcium-independent phospholipase A2β (iPLA2β). It effectively reduces the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells, demonstrating an IC50 of 2 µM. This compound serves as a valuable tool for studying phospholipase activity and its role in various cellular processes.
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