Product Data Sheet

EA4

Catalog No. A77136

main product photo
EA4 is a quinone derivative that acts as an inhibitor of both secretory and cytosolic phospholipase A2 (rPLA and cPLA). It exhibits rPLA2 inhibition with a Ki value of 130 μM, making it a valuable tool for investigating the mechanisms of hemostasis, thrombosis, and erythropoiesis. This compound aids in the study of lipid metabolism and its implications in various physiological and pathological processes.
Chemical Information
Catalog NumA77136
M. Wt340.80
FormulaC19H17ClN2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.389614-94-2
Synonyms
SMILESO=C(C(C1=CC=C(N(CC)CC)C=C1)=C2Cl)C3=C(N=CC=C3)C2=O
Biological Activity
DescriptionEA4 is a quinone derivative that acts as an inhibitor of both secretory and cytosolic phospholipase A2 (rPLA and cPLA). It exhibits rPLA2 inhibition with a Ki value of 130 μM, making it a valuable tool for investigating the mechanisms of hemostasis, thrombosis, and erythropoiesis. This compound aids in the study of lipid metabolism and its implications in various physiological and pathological processes.
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